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Symbol
Name
ID
Kl
klotho
MGI:1101771
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Type II diabetes mellitus
Disease(s) Associated with KL
coronary artery disease

Mouse Phenotypes
dilated gastric gland
abnormal pancreatic beta cell morphology
small pancreatic islets
abnormal adenohypophysis morphology
abnormal gonadotroph morphology
decreased somatotroph cell size
decreased somatotroph secretory granule number
thymus atrophy
absent mature ovarian follicles
ovary atrophy
abnormal seminiferous tubule morphology
testicular atrophy
decreased insulin secretion
Availability Mouse Genotype
Klkl/Klkl
Klm1Anu/Klm1Anu
Klkl/Kl+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory